IKMG SEVENTH INTERNATIONAL MEETING

International Kidney & Monoclonal Gammopathy Research Group

Champalimaud Foundation

Lisbon, Portugal | Sep 26-27, 2025

Paraproteins and Kidney Disease
Immunotherapy and Apheresis
Transplantation

IKMG SEVENTH INTERNATIONAL MEETING

International Kidney & Monoclonal Gammopathy Research Group

Champalimaud Foundation

Lisbon, Portugal | Sep 26-27, 2025

Paraproteins and Kidney Disease Immunotherapy and Apheresis Transplantation

Welcome message

Dear Colleagues,

We are pleased to announce the 7th International Kidney and Monoclonal Gammopathies Meeting, taking place on 26–27 September 2025 in Lisbon, Portugal.

This meeting will bring together leading international experts to explore the latest advances in kidney diseases associated with monoclonal gammopathies. The scientific program will feature sessions on cutting-edge pathophysiological insights, advancements in diagnostic tools, emerging therapeutic strategies, and updates from ongoing clinical trials in the field.

The meeting will also include oral and poster abstract presentations. To promote and recognize scientific excellence, the top three abstracts will be awarded IKMG Scientific Prizes.

The event will be held at the Champalimaud Foundation Auditorium, a unique and inspiring venue located on the banks of the Tagus River.

We warmly invite you to join us in Lisbon for what promises to be an engaging and enriching scientific experience—and a valuable opportunity to connect and exchange ideas with the global IKMG community, both during the sessions and at the social events.

The Organizing Committee,
Karina Soto, Chair of the 7th IKMG Meeting
Virginie Royal and Paulo Lucio, Co-chairs of the 7th IKMG Meeting
Angela Dispenz
ieri, IKMG President

KARINA SOTO

VIRGINIE ROYAL

PAULO LÚCIO

Registration

Registration Type Early Bird Until 1 June Pre-Registration Until 25 September On-Site
MD / Phd
430,50€
(350,00 € + VAT)
553,50 €
(450,00 € + VAT)
615,00 €
(500,00 € + VAT)
Resident / Student / Trainee
123,00 €
(100,00 € + VAT)
246,00 €
(200,00 € + VAT)
430,50€
(350,00 € + VAT)

The amounts shown above include VAT at the legal rate operative in Portugal.

Organizing Committee 7th IKMG Meeting

Executive IKMG Board
President: Angela Dispenzieri 
Vice President: Virginie Royal 
Secretary: Ute Hegenbart 
Treasurer: Nelson Leung

Chair: Karina Soto
Co-chair: Virginie Royal
Co-chair: Paulo Lúcio
Treasurer: Carlos Barreto

Scientific Committee
Frank Bridoux
Nelson Leung
Cristina João

Young Working Group
Afonso Santos
Gonçalo Pimenta

Organizing Committee 7th IKMG Meeting

Chair: Karina Soto
Co-Chair: Paulo Lucio
Co-Chair: Virgine Royal
Treasurer: Carlos Barreto

Scientific Committee 7th IKMG Meeting

Frank Bridoux
Nelson Leung
Cristina João

Young Working Group
Afonso Santos
Gonçalo Pimenta

Faculty

Abhijat Kitchlu | Toronto, Canada
Adriana Garcia-Herrera | Barcelona, Spain
Angela Dispenzieri | Rochester, MN, USA
Arnaud Jaccard | Limoges, France
Ashutosh Wechalekar | London, UK
Bertrand Arnulf | Paris, France
Bruno Paiva | Navarra, Spain
Candice Roufosse | London, UK
Carlos Fernández de Larrea | Barcelona, Spain
Chintan Shah | Gainesville, FL, USA
Christophe Sirac | Limoges, France
Cristina João | Lisbon, Portugal
Eduardo Gutierrez | Madrid, Spain
Eftathios Kastritis | Athens, Greece
Ellen McPhail | Rochester, MN, USA
Emanuele De Simone | Turin, Italy

Enrique Morales | Madrid, Spain
Francesca Lavetelli | Pavia, Italy
Heather Landau | New York, NY, USA
Hugo Ferreira | Porto, Portugal
Jean Paul Fermand | Paris, France
Joana Gameiro | Lisbon, Portugal
José Maximino | Porto, Portugal
Karina Soto | Setúbal, Portugal
Leonor Beleza | Lisbon, Portugal
Luis Quintana | Barcelona, Spain
Maria do Mar Menezes | Lisbon, Portugal
Maria Picken | Chicago, IL, USA
Maria Willrich | Rochester, MN, USA
Mariam Priya Alexander | Rochester, MN, USA
Maria Teresa Cibeira | Barcelona, Spain
Mario Nuvolone | Pavia, Italy

Mohamed Belmouaz | Poitiers, France
Natacha Rodrigues | Lisbon, Portugal
Nelson Leung | Rochester, MN, USA
Paolo Milani | Pavia, Italy
Paul Sanders | Birmingham, AL, USA
Paulo Lúcio | Lisbon, Portugal
Raymond Comenzo | Boston, MA, USA
Rui Bergantim | Porto, Portugal
Sabine Karam | Minneapolis, MN, USA

Samih Nasr | Rochester, MN, USA
Teresa Chuva | Porto, Portugal
Tom Cupedo | Rotterdam, Netherlands
Ute Hegenbart | Heidelberg, Germany
Vaishalli Sanchorawala | Boston, MA, USA
Vecihi Batuman | New Orleans, LA, USA
Virginie Royal | Montreal, Canada

Friday, 26 September

08:30 - 08:45

Opening Session

Leonor Beleza
Angela Dispenzieri

Karina Soto

08:45 - 09:30

Plenary session

Moderators | Paul Sanders, Ute Hegenbart

• From small dangerous B-cell clones to monoclonal gammopathy of renal and clinical significance | Jean Paul Fermand
• Unraveling Proximal Tubule Toxicity of Monoclonal Light Chains: Mechanisms and Implications | Vecihi Batuman
Discussion

09:30 - 10:10

Module 1 - Monoclonal Gammopathy of Renal significance (MGRS)

Mini Lectures & Discussion I
MGUS, SMM, and MM: Current Understanding and Clinical vs. Molecular Basis of MGUS to Myeloma progression. Risk stratification and genomic markers.

Moderators | Angela Dispenzieri, Cristina João

• Unraveling the Journey: Molecular and Clinical Drivers of MGUS and SMM | Tom Cupedo
• Tumor dissemination and immune escape driving myeloma progression | Bruno Paiva
Discussion

10:10 - 11:20

Mini Lecture & Discussion II

Diagnosis of Monoclonal Gammopathy associated kidney lesions: sharing perspective from pathologists

Moderators | Eduardo Gutierrez, Maria Picken

• A new RPS/IKMG consensus on pathologic definitions and terminology of monoclonal gammopathy-associated kidney lesions | Samih Nasr
• British Society for Haematology recommendations for the diagnosis of MGRS: kidney biopsy aspects | Candice Roufosse
• Light chain cast nephropathy – when it is not a myeloma defining event | Virginie Royal
Discussion

11:20 - 11:35

Coffee Break

11:35 - 12:45

Mini Lectures & Discussion III

New strategies to improve the diagnostic performance of MGRS

Moderator | Rui Bergantim

• RNA-based immunoglobulin sequencing as a new tool for MGRS management | Christophe Sirac
• M protein sequencing to detect and follow (small) B cell /plasma cell clones | Mario Nuvolone
• Blood mass spectrometry to detect monoclonal proteins in MGRS | Maria Willrich
Discussion

12:45 - 13:40

Mini Lecture & Discussion IV

State of the Art in Treatment Approaches of MGRS

Moderators | Arnaud Jaccard, Paulo Lúcio

• Old and New in Clone-Directed Therapies for MGRS | Angela Dispenzieri
• Supportive management for MGRS | Luis Quintana
• Innovative pipeline therapies for MGRS | Nelson Leung
Discussion

13:40 - 15:00

Lunch Break

15:00 - 15:20

Young Investigation Award - Oral Communication

Moderators | Angela Dispenzieri, Karina Soto

Discussion

15:20 - 15:45

Module 2 - MM and other Hematologic Disorders

MINI LECTURES & DISCUSSION V
• Renal diseases related to Hematologic Disorders beyond
Monoclonal Gammopathies | Mariam Priya Alexander

Moderators | Adriana Garcia-Herrera, Virginie Royal

Discussion

15:45 - 16:40

Mini Lectures & Discussion VI

Extracorporeal FLC removal in Light Chain Cast Nephropathy

Moderator | Enrique Morales

• Plasma exchange: The Mayo Clinic experience | Nelson Leung
• Are there efficient alternatives to high cut-off HD? | Mohamed Belmouaz
• Removal of FLC through dialysis: adsorption with HFR supra system | Emanuele De Simone
Discussion

16:40 - 17:00

Coffee Break

17:00 - 17:50

Mini Lectures & Discussion VII

Treating the clone and Managing Treatment toxicity

Moderators | Abhijat Kitchlu, Efstathios Kastritis

• How to use new therapeutic tools against MM to target the clone in monoclonal gammopathy of clinical significance | Bertrand Arnulf
• Targeted immunotherapies through Anti-BCMA–targeted approaches and Bispecific CAR T-cell therapies | Carlos Fernández de Larrea
Discussion

17:50 - 18:10

Clinical Cases

Moderators | Abhijat Kitchlu, Joana Gameiro

Saturday, 27 September

09:00 - 10:30

Module 3 - Amyloidosis and Transplatation

Mini Lectures & Discussion VIII
Diagnosis and therapeutic innovation in AL Amyloidosis

Moderators | Vaishalli Sanchorawala, José Maximino

• Mechanisms understanding of renal amyloidosis | Francesca Lavetelli
• The Utility of Mass Spectrometry-based Proteomics in the Diagnosis of Renal Amyloidosis: Lessons Learned from Analysis of 5,000+ Cases | Ellen McPhail
• Transcriptional profiling and novel histologic scoring tool | Raymond Comenzo
• Novel therapeutic approach | Ashutosh Wechalekar
Discussion

10:30 - 11:30

Mini Lectures & Discussion IX

Assessing eligibility, outcomes and challenges in kidney and SC transplantation

Moderators | Luis Quintana, Ute Hegenbart

• Kidney transplantation in patients with MGRS, MM and Amyloidosis | Heather Landau
Eligibility for Stem Cell Transplantation in Monoclonal Gammopathies with CKD | Maria Teresa Cibeira
Discussion

11:30 - 11:45

Coffee Break

11:45 - 12:25

Clinical Cases

Moderators | Abhijat Kitchlu

Co-moderators | Hugo Ferreira, Maria do Mar Menezes, Natacha Rodrigues, Teresa Chuva

12:25 - 13:40

Module 4 - IKMG Business Meeting

IKMG Registries

Angela Dispenzieri
• MGRS Registry | Sabine Karam

IKMG New and Ongoing Projects

• Collaborative research projects | Nelson Leung
• Incidence, Clinical Features, and Outcomes of Proliferative
GN with Monoclonal Immunoglobulin Deposition with
Detectable Clone – A Study Proposal | Chintan Shah
• MIDD international study | Paolo Milani

13:40 - 14:00

Closing Session

Sponsors

Sponsorship requests: secretariado@factorchave.pt

The International Kidney and Monoclonal Gammopathy Research Group is dedicated to uniting world-renowned specialists in renal diseases caused by monoclonal proteins. Our mission is to advance the understanding of the clinical pathology, diagnosis and treatment strategies for renal diseases associated with gammopathy and to explore innovative therapeutic approaches through interdisciplinary collaboration. We anticipate the participation of 400 experts at this event.

Scientific Sponsors

Opinions expressed by the authors, do not necessarily reflect the position of the S.E.N.

GT Onconefrologia

Institutional Sponsors

Abstracts

Rules for submission

Please read the submission rules before submitting an abstract.
• Abstracts will be collected by online abstract system.
• Abstracts must be received by the announced deadline. Abstracts received after the deadline will not be considered.
• All abstracts should be submitted and presented in clear English with accurate grammar and spelling of a quality suitable for publication.
• The authors should ensure that the patient consent is obtained before submitting the abstract.
• Only abstracts with results will be accepted for review. Abstracts stating “data will be discussed in the presentation” will NOT be accepted.
• Presenting authors must be registered participants.
Note: Abstracts of already published articles will not be considered.

Abstract Categories
1. Research Abstracts
Among the submitted abstracts, the best research abstract will be presented as an oral communication during the IKMG meeting and will be rewarded the “Young Investigation Award” (500€). The second and third best research abstracts will be also rewarded (300€ and 200€, respectively).
2. Clinical Cases
Among the submitted abstracts, the 3 best abstracts will be presented as an oral communication during the IKMG meeting, with a specific Certificate.

Abstract Structure
Research Abstracts should follow this structure:
• Background
• Materials and Methods
• Results
• Discussion and conclusion

Clinical Cases should follow this structure:
• Background
• Case description
• Discussion and learning points

General structure:
• The abstract must not exceed 250 words. Title, authors’ names, affiliations, references, tables and figures are not included in the word count.
• The abstract may include up to 2 visual elements (Tables and/or Figures), and they must be referenced in the text and numbered in the order they appear. All tables and figures must be accompanied by a caption and list of abbreviations whenever appropriate (e.g., Table 1: description / Figure 1: description).
• The authors’ affiliation should be clearly indicated as follows: Department, Institution, City, Country (e.g., Department of XXXXX, University of XXXX, Lisbon, Portugal). Please note that the country names should be spelled in English.
• Abstract title – must be in UPPER CASE and limited to 25 words. Please submit symbols as words (e.g. Beta, alpha, etc.).
• You may enter up to 3 keywords, separated by commas (e.g., word 1, word 2, word 3)
• Abbreviations and acronyms should be spelled in full and followed by the abbreviation/acronym in a parenthesis the first time they are mentioned in the abstract (e.g. Monoclonal gammopathy of renal significance (MGRS)).
• Use generic names of drugs in small letters and not trade names. Abstract content must be scientifically valid, objective and balanced and contain no commercial promotional content.
• Do not include patient names within the text or visual elements, as well as any hospital patient ID codes or other details that could potentially reveal patient identities. Figures showing patients faces should be modified and, at least, eyes should be covered or blurred.

In order to submit an abstract, you will be required to create a login, to access the submission platform. Please note that in case you have already submitted an abstract or participated in other event organized by FactorChave, there is a possibility that your user is already registered. If you by any chance won’t be able to login with a preferential e-mail because of this situation, kindly contact us through secretariado@factorchave.pt or (+351) 21 430 77 40.

Book of Abstracts

More information soon.

About Lisbon

Lisbon, Portugal’s capital, is a captivating mix of old-world charm and contemporary energy. Known for its historic neighborhoods, iconic yellow trams and stunning viewpoints, it offers a unique blend of culture, history and modernity. With its vibrant food scene, rich heritage and proximity to the Tagus River, Lisbon is a city that enchants visitors with its warmth and authenticity.

Climate

The climate in Lisboa is temperate, offering the best of both Atlantic and Mediterranean breezes throughout the year. The average temperature in winter is about 17°C/ 62°F. The average temperature in summer is about 26°C/ 79°F.

Currency

The official currency of Portugal is the euro (€).

‍Electric Current

The Portuguese standard is the European 2-pin socket with 220 volts AC at 50 cycles

Local Time

Mainland Portugal is 1 hour behind Central European Time (CET – 1).

Language

The official language in Portugal is Portuguese. English, Spanish, and French are also widely spoken.

Medical Care

Clinics and hospitals provide 24-hour emergency service.

The national emergency phone number is 112. Hotels have a doctor on call through the reception.

Smoking

The Portuguese law, in accordance with regulations in force in the majority of European Union member states, does not allow smoking in public transportation or in any closed public areas. However, some restaurants, bars, and clubs may have designated smoking areas.

TAX Free

Sales tax (VAT) is included in prices quoted. For persons who are not residents of the European Union, tax-free shopping schemes are available in many shops, giving substantial savings to visitors.

Features of Lisbon

The Jerónimos Monastery was proclaimed a UNESCO World Heritage Site in 1983. This notable 16th century work of architecture became part of Portuguese identity and culture
Museu Nacional de Arte Antiga houses the most relevant public collection, from the 12th to the 19th century. Painting, sculpture, silver, gold and jewellery, decorative arts – Portuguese, European, African and Oriental.
Museu Nacional do Coches The museum houses a unique collection in the world consisting of vehicles from the 17th, 18th and 19th centuries including coaches, berlins, sedan chairs and carriages.
Arco da Rua Augusta Climb up one of Lisbon’s iconic buildings for a unique view of the city. Open to the public since 9 August 2013, the Arch leaves Lisbon at your feet, literally.

Visa Information

A visa may be acquired online or in person at a Portuguese embassy or consulate.
For a complete list of countries whose citizens are required to obtain a Schengen visa, please check: https://vistos.mne.gov.pt/en/

Invitation letter
A customized invitation letter for visa purposes is available for delegates with a confirmation that registration has been paid in full. Please send your request to the Congress secretariat: secretariado@factorchave.pt

Accommodation & Travel

For personalize offers or hotels suggestions, kindly contact the congress secretariat through secretariado@factorchave.pt.

For more information about hotels and sight seeing’s please visit the official website of the Lisbon’s Tourism office (visitlisboa.com)

Hotel Check in/out Policy
Normal check in time at hotels is 15h00. The established check out time is 12h00. Should you need guaranteed occupancy before 13h00 on the day of your arrival, the previous night should be reserved. ‍
Please note that it may differ among hotels. Check your booking information in advance.

Getting to Lisbon & local transportation

Lisbon is the main city of Portugal, situated right in the centre of the country in the northern margin of the river Tagus. Its International airport is at 15 minutes from the city centre and from all the main hotels. The most important European Airlines, as well as some North America Airlines, operate direct daily flights to Lisbon, from the most important European Capitals and North America. For delegates making intercontinental flights, the best connecting hubs in Europe are Amsterdam, Munich, Zurich, Frankfurt, Paris, Brussels, Madrid or London.

By Air
Lisbon International Airport, 7 km from the city centre, has daily flights to and from the major cities in Europe and the world. The Portuguese airline TAP – Air Portugal, as well as major international airlines, fly to and from Lisbon.

Destinations and companies that fly to Lisbon:
Lisbon is easy to get to. It is a short flight away from most European cities.
https://www.aeroportolisboa.pt/en/lis/flights-destinations/airlines/airlines-and-destinations

By Rail
Scores of national and international trains arrive in Lisbon every day. In addition to Santa Apolónia terminal station, the city has also the Gare do Oriente, which opened in 1998 adjacent to the Parque das Nações. Both stations have direct bus or underground connections to the city centre.

By Road
Arriving in Lisbon by road is a pleasant experience, as the visitor can enjoy the beautiful countryside along the way. The city has good road accesses and the most frequently used routes are: the A1 motorway, the 25th April Bridge, the new Vasco da Gama Bridge, and the CREL, the outer ring-road for the Lisbon region.

Getting around in Lisbon
There is a wide inexpensive network in all towns and cities. In Lisbon, city of the seven hills, you can choose between bus, underground metro, elevators, and electric trams, within the city or to the suburbs. Trains and express bus service also links the main towns of the country.

From the Airport
Once landed at Lisbon’s Airport, a scheduled bus is operating regular transfers between the Airport and the city centre. Catching a taxi is easy and from Lisbon’s airport to the city centre it will cost approximately € 10.

Uber
Uber is available in Lisbon and operates effectively. Download the app to get around.
https://www.uber.com/pt/en/

Taxi voucher
Service at the Lisbon Airport – courtesy, friendliness, and safe driving.
This service is available to passengers arriving at Lisbon Airport who wish to travel by taxi.
The service operates with vouchers on sale at the Turismo de Lisboa counter, located in the Arrivals Hall. The price of the voucher depends on the distance of the trip and on the type of service required: normal or personalized (in the former, the driver is trained to speak foreign languages and acts as tourist guide).

Detailed information regarding public transportation is available at:
carris.pt for trams and buses
metrolisboa.pt for metros

Scientific Organizer

Official Organizer

Official Agency